目的 分析不同年龄层次疑似肺 癌患者行低剂量CT扫描的筛查结果，探讨 低剂量CT扫描的临床应用价值。方法 选 取2016年1月-2017年1月收治的疑似肺癌 患者154例进行回顾性分析。按照患者年 龄分3组，30岁以下组(45例)，30-55岁 (52例)，55岁以上(57例)，分别进行低剂 量CT扫描和病理检测。以病理检测结果为 金标准，观察低剂量CT诊断肺癌的灵敏 度、特异度、准确度及Kappa值；观察比 较不同年龄段肺癌患者使用低剂量CT后肺 结节检出情况；比较不同年龄段肺癌患者 肿瘤生长部位及病理类型差异。结果 低 剂量CT诊断肺癌的灵敏度为0.893，特异 度为0.900，准确度为0.896，Kappa值为 0.791；三个年龄段组均检出实质性、部 分实质、非实质性结节，不同年龄段患者 实质性结节检出率比较(P<0.05)，部分实 质和非实质性结节检出率比较(P>0.05)； 低年龄段肺癌患者的肿瘤以周围型居多， 高年龄断肺癌患者的肿瘤以中央型居多， 生长部位比较(P<0.05)；低年龄段肺癌患 者以腺癌居多，高龄段肺癌患者以鳞癌居 多，癌症类型比较(P<0.05)。结论 低剂 量CT诊断肺癌的准确度较高，对不同年龄 段肺癌患者肺结节类型、肺癌患者肿瘤生 长部位和类型可做出较为准确的诊断。

Objective To analyze the screening results of low-dose CT scan in patients with suspected lung cancer at different ages and explore the clinical application value of lowdose CT scan. Methods 154 cases of patients with suspected lung cancer admitted between January 2016 and January 2017 were retrospectively analyzed performed. According to the patient's age, they were divided into three groups, including below 30 years old (45 cases), 30-55 years old (52 cases), and above 55 years old (57 cases) respectively. And they were given low-dose CT scan and pathological examination. The pathological test results were used as the gold standard to observe the sensitivity, specificity, accuracy and Kappa value of low-dose CT in the diagnosis of lung cancer. The detection of lung nodules by lowdose CT were observed among patients with different age groups. And the tumor growth sites and pathological types were compared among patients with lung cancer at different age groups. Results The sensitivity, specificity, accuracy and Kappa value of low-dose CT in the diagnosis of lung cancer were 0.893, 0.900, 0.896 and 0.791. Solid nodules, partial solid nodules and non-parenchymal nodules were detected in all age groups, and there was a difference in the detection rate of solid nodules (P<0.05), and there was no difference in the detection rates of partial solid nodules and non-parenchymal nodules (P>0.05). The tumors of patients with low-age lung cancer were mostly peripheral type, and the tumors of patients with high-age lung cancer were mostly central type, and there was a difference in growth sites (P<0.05). The patients with low-age lung cancer were mostly adenocarcinoma, and the patients with high-age lung cancer were mostly squamous cell carcinoma, and there was a difference in cancer types (P<0.05). Conclusion Low-dose CT has high accuracy in the diagnosis of lung cancer. It can make an accurate diagnosis of lung nodules types, tumor growth sites and types of lung cancer patients with different age groups.