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能谱CT对肺内占位 良恶性鉴别及诊断 价值

作者:姚鹏鹏 李润涛

所属单位:河南省郑州市中心医院 (河南 郑州 450003)

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摘要

目的 探讨能谱CT对肺内占位良 恶性的鉴别及诊断价值。方法 选择我院 2015年3月至2017年10月经影像学检查(X 线、CT)发现肺内占位的57例患者作为研 究对象,根据病理检查结果将其分为良性 占位组(n=21)和恶性占位组(n=36)。两组 患者均实施能谱CT成像技术,并对图像 进行分析处理,对比两组动、静脉期40- 80keV隔间单能量CT值,动脉期40-70keV 期间能谱斜率,动、静脉期碘和水基值及 差值。结果 动、静脉期40-80keV隔间单 能量CT值及动脉期40-70keV期间能谱斜 率,良性占位组均低于恶性占位组,差异 有统计学意义(P<0.05)。动、静脉期碘 基值及差值,良性占位均低于恶性占位, 差异有统计学意义(P<0.05);动、静脉 期水基值及差值,良性占位均高于恶性占 位,差异有统计学意义(P<0.05)。结论 肺内占位良恶性在能谱CT表现上存在一定 差异,其诊断结果对临床诊断具有一定参 考价值。

Objective To explore the identification and diagnostic value of energy spectrum CT for benign and malignant lung lesions. Methods A total of 57 patients with pulmonary lesion examined by X-ray and chest CT from March 2015 to October 2017 were selected for the study. According to the pathological examination results, the patients were divided into benign lesion group (n=21) and malignant lesion group (n=36). The two groups were given energy spectrum CT imaging technique, and the images were analyzed and processed. The single-energy CT values of 40-80 keV compartments in arterial and venous phases, and the energy spectrum slope of 40-70 keV compartments in arterial phase, iodine base value and water base value and difference in arterial and venous phases were compared between the two groups. Results The single-energy CT values of 40-80 keV compartments in arterial and venous phases were lower in benign lesion group than those in malignant lesion group (P<0.05). There was a statistically significant difference in the energy spectrum slope of 40-70 keV compartments in arterial phase (P<0.05). The iodine base value and difference in arterial and venous phases were lower in benign lesion group than those in malignant lesion group (P<0.05). The water base value and difference in arterial and venous phases were higher in benign lesion group than those in malignant lesion group (P<0.05). Conclusion There are some differences in the energy spectrum CT findings of benign and malignant lung lesions. CT diagnostic results have certain reference value for clinical diagnosis.

【关键词】能谱CT;肺部肿瘤;诊断价值

【中图分类号】R734.2

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2019.04.015

前言

肺癌是常见肺部原发性恶性肿瘤,相关研究发现,男性肺癌是所 有恶性肿瘤发病、死亡率之首,而女性肺癌发病、死亡率居于第二, 且城市居民发病率明显高于农村[1]。随着经济和人均压力不断升高, 环境污染日益加剧、吸烟人群增多、雾霾等各种天气状况层出不穷, 肺部疾病出现多样变化,部分良性肿瘤在影像学检查时与肺癌表现相 似,且部分肺部良性病变亦会发展为肺癌[2]。肺癌早期症状不明显, 目前影像学诊断多以形态学为主,诊断难度较高,肺部组织病理学诊 断仍是金标准[3]。能谱CT成像技术作为一种新型成像模式,可对组织 成分进行定量分析,本文将其应用于肺内占位性病变患者良恶性肿瘤 的鉴别,并探讨其诊断价值,现将研究结果报道如下。