目的 分析多层螺旋CT(MSCT)诊 断非结核分枝杆菌(NTM)肺病的临床价 值。方法 将我院2014年1月-2018年12月 收治的59例NTM肺病患者设NTM肺病组；另 按1:1比例筛选同期收治的肺结核病患者 59例设肺结核组，比较两组病灶分布及 MSCT征象，并建立二元Logistic回归预测 模型，分析MSCT征象对NTM肺病的诊断价 值。结果 NTM肺病组中，病灶分布于Ⅱ区 患者比重显著高于肺结核组(P＜0.05)； 且NTM肺病组中出现支气管扩张、支气 管狭窄或闭塞、肺毁损征象患者比重显 著高于肺结核组，而出现腺泡结节、实 变征象患者比重则显著低于肺结核组(P ＜0.05)；经二元Logistic回归分析，支 气管扩张、支气管中心狭窄、小叶中心性 结节、肺损毁是NTM肺病的独立危险因素 (P＜0.05)；将上述因子纳入预测模型后 行ROC曲线分析，MSCT诊断NTM肺病的灵 敏度为88.10%、特异度为83.10%。结论 MSCT检查合并支气管扩张、支气管中心狭 窄、小叶中心性结节、肺损毁等征象或提 示NTM肺病，应引起临床重视。

Objective To analyze the clinical value of multi-slice spiral CT (MSCT) in the diagnosis of nontuberculous mycobacteria (NTM) lung disease. Methods 59 patients with NTM lung disease admitted to the hospital from January 2014 to December 2018 were enrolled in the NTM lung disease group. The other 59 patients with pulmonary tuberculosis admitted in the same period were enrolled in pulmonary tuberculosis group. The distribution of lesions and MSCT signs in the two groups were compared. Binary Logistic regression prediction model was established. The diagnostic value of MSCT signs for NTM lung disease was analyzed. Results In the NTM lung disease group, the proportion of patients with distribution of lesions in the II area was significantly higher than that of the pulmonary tuberculosis group (P<0.05). The proportion of patients with bronchiectasis, bronchoconstriction or occlusion and lung damage was significantly higher than that of the pulmonary tuberculosis group, while the proportion of patients with acinar nodules and consolidation was significantly lower than that of pulmonary tuberculosis group (P<0.05). Binary Logistic regression analysis showed that bronchiectasis, bronchial center stenosis, centrilobular nodules and lung damage were independent risk factors for NTM lung disease (P<0.05). After the above factors were included in the predictive model, the analysis of ROC curve was performed. The sensitivity and specificity by MSCT for diagnosis of NTM lung disease were 88.10% and 83.10%, respectively. Conclusion MSCT examination combined with the signs of bronchiectasis, bronchial center stenosis, centrilobular nodules and lung damage may indicate NTM lung disease.