论著-头颈部
17例股骨骨肉瘤患者CT与MRI影像学特征及诊断价值研究
作者:陈 婧1 韩星敏2
所属单位:1.郑州市骨科医院放射科(河南 郑州 450000) 2.郑州大学第一附属医院核医学科(河南 郑州 450052)
PDF摘要
目的探讨股骨骨肉瘤CT与MRI的 影像学特征及其诊断价值。方法 选取我 院2014年11月-2017年10月股骨骨肉瘤患 者17例,均接受病理学检查、CT检查及 MRI检查。统计对比CT及MRI对股骨骨肉瘤 及股骨骨肉瘤相关征象(Codman三角、软 组织肿块、骨膜反应、瘤骨、骨质破坏) 诊断准确率,并分析本组患者病理、CT及 MRI表现。结果 MRI对股骨骨肉瘤诊断准 确率(94.12%)较CT(82.35%)高,但差异 无统计学意义(P>0.05);MRI对Codman 三角诊断准确率(41.18%)较CT(64.71%) 低,但无明显差异(P>0.05),MRI对软组 织肿块、骨膜反应、骨质破坏诊断准确 率(94.12%、88.24%、100.00%)较CT高(P <0.05),MRI对瘤骨诊断准确率(58.82%) 较CT低(P<0.05)。结论 采取CT及MRI可 对股骨骨肉瘤及其相关征象予以准确诊 断,对疾病的早期诊断和病变范围的显示 具有显著优势,可为临床及早制定针对性 干预方案提供一定参考依据。
Objective To investigate the imaging features and diagnostic value of CT and MRI in femoral osteosarcoma. Methods A total of 17 patients with femoral osteosarcoma in our hospital from November 2014 to October 2017 were selected for pathological examination, CT and MRI examination. The diagnostic accuracy of CT and MRI for femoral osteosarcoma and related features of femoral osteosarcoma (Codman triangle, soft tissue mass, periosteal reaction, tumor bone and bone destruction) was compared statistically. The pathological features, CT and MRI findings of the patients were analyzed. Results The diagnostic accuracy of MRI for femoral osteosarcoma (94.12%) was higher than that of CT (82.35%), but the there was no statistically difference(P>0.05). The diagnostic accuracy of MRI for Codman triangle (41.18%) was lower than that of CT (64.71%), but there was insignificant difference between them(P>0.05). The diagnostic accuracy of MRI for soft tissue mass, periosteal reaction and bone destruction (94.12%, 88.24%, 100%) was higher than that of CT(P<0.05). The diagnostic accuracy of MRI for bone tumors (58.82%) was lower than that of CT(P<0.05). Conclusion CT and MRI can be used for diagnosis of femoral osteosarcoma and its related signs, which has significant advantages in the early diagnosis and the determination of the scope of invasion. It can provide certain reference for the early clinical development of targeted intervention programs.
【关键词】股骨骨肉瘤;CT;MRI;影像学特征;诊断价值
【中图分类号】R814.42;R738.7
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.12.040
前言
骨肉瘤为临床原发性恶性骨肿瘤疾病,起源于成骨性间叶组织, 占恶性肿瘤总发病率的0.2%左右、占原发性骨肿瘤总发病率的11.7% 左右,在青少年及儿童群体、男性中发病率较高,,具有较高恶性程 度,且预后较差[1-2]。此外,骨肉瘤好发于股骨下端,若肿瘤蔓延至骨 膜下,则骨膜可被肿瘤自骨面剥离而形成反应性新生骨,骨干和肿瘤 连接部位的新生骨多呈三角形,临床实际中易误诊为纤维瘤、软骨肉 瘤等[3-4]。同时,由于股骨骨肉瘤恶性程度高,进展快,早期确诊、明 确肿瘤范围及侵犯程度对改善临床疗效及预后具有重要意义。传统多 采用X线平片对股骨骨肉瘤予以诊断,简便易行,但难以准确确定病变 范围,随着影像学技术不断发展,CT及MRI在临床多种疾病诊断及疗效 评估中得到推广应用,并取得了一定效果[5-7]。本研究选取我院17例股 骨骨肉瘤患者,探讨股骨骨肉瘤CT与MRI的影像学特征及其诊断价值。 如下报告。
中国CT和MRI杂志
第16卷, 第 12 期
2018年12月
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