目的探讨PI-RADS V2结合MRI 诊断外周带前列腺癌(PCa)的价值。方 法 23例经病理证实的PCa患者行MRI检 查，分析T2WI、DWI、DCE图像，按照6 分区法对前列腺外周带各分区进行评 分。分析MRI的T2WI、DWI、T2WI+DWI及 T2WI+DWI+DCE4种方案对外周带前列腺癌 诊断的灵敏度、特异度和准确率，绘ROC 图。结果 23例PCa共分138个区，PCa为 67个区，非PCa为71个区，67个癌区t值 分别为(4.29±0.85)，(4.34±0.79)， (4.49±0.61)，(4.59±0.55)；71 个非癌区t值分别为(2.69±0.89)， (2.89±1.10)，(2.97±0.95)， (2.59±0.78)，各组PCa区与非PCa区评 分的差异均有统计学意义(P<0.05)。基 于PI-RADS v2的mp-MRI诊断外周带PCa 的敏感性、准确率、AUC均高于T2WI、 DWI、DCE。结论 基于PI-RADS v2的mpMRI对外周带PCa具有较高的诊断价值。

Objective To investigate the value of PI-RADS V2 combined with MRI in the diagnosis of peripheral prostate cancer (PCa). Methods A total of Twenty-three patients undergoing MRI examination were analyzed for T2WI, DWI, and DCE images. The subarea of the prostate peripheral zone was scored according to the 6-partition method. T-tests were performed on MRI of T2WI, DWI, T2WI+DWI, and T2WI+DWI+DCE. Calculate the sensitivity, specificity, and accuracy of T2WI, DWI, DCE, and PI-RADSv2 based MRI diagnostic peripheral zones, and plot ROC plots. Results A total of 23 cases of PCa were divided into 138 areas, with 67 areas of PCa, 71 areas of non-PCa, the t values of the PCa area were (4.29±0.85), (4.34±0.79), (4.49±0.61), (4.59±0.55) respectively, and the t values of non-PCa area were (2.69±0.89), (2.89±1.10), (2.97±0.95), (2.59±0.78) respectively. There was a significant difference in the PCa and non-PCa scores between the two groups (P<0.05). The sensitivity, accuracy, and AUC of PIRADS v2-based peripherial PCa diagnosis were higher than those of T2WI, DWI, and DCE. Conclusion Mp-MRI diagnosis based on PI-RADS V2 has high diagnostic value for peripheral PCa.