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MPR在中央型及周围型肺癌诊断中的价值研究*

作者:梁 琰 张永强 李展展 朱绍成

所属单位:河南省三门峡市中心医院CT诊断中心(河南 三门峡 472000)

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摘要

目的探讨多层螺旋CT多平面重 建(MPR)影像处理技术在中央型及周围型 肺癌中的诊断价值。方法 收集我院近一 年半诊治的经支气管病理或手术病理证 实的96例肺癌(包括中央型52例,周围型 44例)病人术前CT影像资料,比较患者常 规横断面薄层扫描图像及MPR重建图像 对肺癌的显示效果,并探讨MPR影像处 理技术在中央型及周围型肺癌中的诊断 价值。结果 (1)横断面薄层扫描及MPR 测得的中央型肺癌叶、段支支气管管壁 平均厚度(T)分别为(8.01±1.24)mm和 (14.71±3.58)mm,管壁增厚平均长度(L) 分别为(14.16±2.79)mm和(22.54±4.57) mm,T/L比值分别为0.56和0.62;横断面 薄层扫描图像及MPR重建图像测得的中央 型肺癌叶、段支支气管管壁增厚T、L差异 显著(P<0.05)。(2)横断面薄层扫描显示 周围型肺癌短毛刺征35例、深分叶征28 例、空泡征20例、支气管血管集束征30 例、胸膜凹陷征30例、空气支气管征19 例;MPR显示周围型肺癌短毛刺征40例、 深分叶征35例、空泡征22例、支气管血管 集束征41例、胸膜凹陷征38例、支气管充 气征37例;横断面薄层扫描及MPR对周围 型肺癌的深分叶征、支气管血管集束征、 空气支气管征、胸膜凹陷征显示有显著差 异(P<0.05)。结论 MPR对中央型肺癌及周 围型肺癌病变显示更清晰,有助于提高肺 癌的CT诊断准确率,指导临床制定合理的 手术方案,提高肺癌患者的治疗效果。

Objective To investigate the value of multi-slice spiral CT multi-planar reconstruction (MPR) in the diagnosis of central and peripheral lung cancer. Methods The preoperative CT imaging data of 96 patients with lung cancer (including 52 cases of central type and 44 cases of peripheral type) which confirmed by transbronchial pathology or surgical pathology in our hospital for nearly one and a half years were collected. The display effects of conventional trans-axial thin-layer scan images and MPR reconstructed images on lung cancer were compared, and the diagnostic value of MPR was analyzed in central and peripheral lung cancer. Results The mean thickness (T) of bronchial and bronchial branches of central lung cancer were (8.01±1.24) mm and (14.71±3.58) mm measured by trans-axial thin-layer scan and MPR respectively, and the average length (L) of tube wall thickening were (14.16±2.79) mm and (22.54±4.57) mm respectively, and the T/L ratio were 0.56 and 0.62 respectively, and there were significant differences in the T and L of tube wall thickening of central lung cancer leaf and segmental bronchial branches measured by transaxial thin-layer scan images and MPR reconstruction images (P<0.05). Transaxial thin-layer scan showed there were 35 cases of short spurs in peripheral lung cancer, 28 cases of deep lobulated sign, 20 cases of vocule sign, 30 cases of bronchial vascular bundle sign, 30 cases of pleural indentation and 19 cases of air bronchogram. MPR showed there were 40 cases of short spurs in peripheral lung cancer, 35 cases of deep lobulated sign, 22 cases of vocule sign, 41 cases of bronchial vascular bundle sign, 38 cases of pleural indentation and 37 cases of air bronchogram. There were significant differences in the deep lobulated sign, bronchial vascular bundle sign, air bronchogram and pleural indentations of peripheral lung cancer by transaxial thin-layer scan and MPR (P<0.05). Conclusion MPR can show the lesions of central and peripheral lung cancer more clearly, which help to improve the accuracy of CT diagnosis of lung cancer, and guide the clinical formulation of a reasonable surgical program, and improve the treatment effect of lung cancer.

【关键词】中央型肺癌;周围型肺癌; 薄层CT;多平面重建;三维重建;X线计算机

【中图分类号】R734.2

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.12.017

前言

支气管肺癌(简称肺癌)是指起源于支气管粘膜或腺体的癌症,发 病率及死亡率均为恶性肿瘤首位,近年来发病率明显增高,每年约有 138万人死于肺癌[1]。肺癌的临床分类及分型方法很多,按肿瘤的发 生部位大体可分为中央型肺癌和周围型肺癌,中央型肺癌指发生在肺 段及段以上支气管,约占肺癌的3/4,周围型肺癌发生在肺段以下支 气管,约占1/4[2]。肺癌早期常无明显症状,75%的患者确诊时已到晚 期,提高肺癌的检出率具有重要的意义。CT扫描目前是肺癌的最佳影 像检查手段,常用于肺癌的术前分期及术后随访,包括薄层扫描、高 分辨率CT(HRCT)扫描、动态增强、靶CT扫描、双能CT扫描及各种后处 理技术等。多平面重建(MPR)属于后处理技术中的一种,是将扫描范围 内的轴位图像叠加起来再对某些标线标定的重组线所指定的组织进行 冠状位、矢状位及任意角度斜位图像重组[3]。本文研究MPR重建图像对 中央型肺癌及周围型肺癌的显示效果,分析MPR后处理技术对肺癌的的 诊断价值,旨在寻求更多有效途径提高肺癌的检出率。