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65例儿童腺病毒肺炎临床特征及其CT影像学表现*

作者:李少宁1 郑方芳2 符 佳1 刘 涛3

所属单位:1.陕西省西安市儿童医院急诊科(陕西 西安 710003) 2.中山大学附属第五医院儿科(广东 珠海 519000) 3.陕西省西安市儿童医院感染科(陕西 西安 710003)

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摘要

目的分析65例儿童腺病毒肺炎 的临床特征及其CT影像学表现。方法 回 顾性分析2017年5月-2018年4月本院收治 的65例腺病毒肺炎儿童临床资料,均行CT 扫描检查,分析研究对象的临床特征及其 CT影像学表现。结果 儿童腺病毒肺炎四 季皆可发,尤以冬季发病率最高,其起病 急促,高热持续时间长,多表现为稽留 热、弛张热、精神萎靡、面色不佳和中毒 症状,患儿发热温度在40.0-40.9℃范围 内几率最高,以发热、肺部湿啰音症状、 哮鸣音为主要临床特征,抗生素加抗病毒 药物为其常见治疗方案;CT影像学检查提 示肺部以肺实质散在斑片状密度增高影, 双肺受累常见,肺外表现为胸腔积液,小 气道充气不均匀。结论 腺病毒肺炎儿童 临床特征及其CT影像学表现有一定特点, 临床可据此对腺病毒肺炎患儿进行鉴别诊 断,对降低患儿病死率有一定积极作用。

Objective To analyze the clinical features and CT imaging findings of 65 children with adenovirus pneumonia. Methods The clinical data of 65 children with adenovirus pneumonia who were admitted to the hospital from May 2017 to April 2018 were analyzed retrospectively. CT scan was performed, and the clinical features and CT imaging findings of the subjects were analyzed. Results Adenovirus pneumonia could occur in all seasons, especially in winter. Its onset was rapid, and the duration of fever was long. It was characterized by continuous fever, remittent fever, spirits apathy, poor complexion and symptoms of poisoning. The probability of temperature in the range of 40.0-40.9°C was the highest. The main clinical features included fever, pulmonary moist rales and wheezing. Antibiotics plus antiviral drugs were common regimens. CT imaging examination showed lung parenchyma was scattered in the shadow of increased density, both lungs affected, pleural effusion outside the lungs and uneven air inflation in the small airway. Conclusion The clinical features and CT imaging findings of children with adenovirus pneumonia are characteristic. Clinically, children with adenovirus pneumonia can be accurately diagnosed and differentiated, which has a positive effect on reducing the mortality of children.

【关键词】腺病毒肺炎;儿童;临床特征;CT影像学表现

【中图分类号】R563;R814

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.12.015

前言

腺病毒肺炎属于儿科常见呼吸系统疾病,一直以来临床对腺病毒 肺炎的治疗尚缺乏行之有效的药物方案,患儿死亡率较高,随着国内 医疗设备不断完善及医疗技术不断提高,儿童腺病毒肺炎的临床治疗 效果得以明显改善,患儿死亡率得以有效控制,长期临床实践表明腺 病毒肺炎的传染性及死亡率较高[1-2]。在婴幼儿阶段,腺病毒肺炎在重 症肺炎中所占比例高达20.0%左右,是引起患儿发生肺部感染的重要原 因[3],鉴于临床对本病治疗效果欠佳,有必要积极探究儿童腺病毒肺炎 的临床特征及其影像学表现,对提高本病早期准确诊断率有重要临床 意义,利于合理防治方案的制定[4]。本文对2016年1月-2018年1月本院 收治的65例腺病毒肺炎儿童临床资料进行回顾性分析,旨在探讨儿童 腺病毒肺炎患者早期鉴别诊断标准。