目的探讨多层螺旋CTA与超声造 影(CEUS)联合应用在颈动脉斑块稳定性 评估中的临床应用。方法 选取2017年2 月至2018年5月我院收治的颈动脉斑块狭 窄患者共120例，先后进行颈动脉CTA、 CEUS检查，观察患者颈动脉斑块情况。结 果 以病理检测结果为金标准，120例颈 动脉斑块CEUS检查的准确度88.33%，灵敏 度72.73%,特异度94.25%，Kappa=0.70，P ＜0.05；CTA检查的准确度81.66%，灵敏 度60.00%,特异度90.59%，Kappa=0.533， P＜0.05；CTA与CEUS联合检查的准确度 91.67%，灵敏度78.79%,特异度96.55%， Kappa=0.783，P＜0.05；CTA联合CEUS评 估颈动脉斑块稳定性，其准确度、灵敏 度、特异度、阴性预测值、阳性预测值均 高于单独CTA与单独CEUS检测。结论 多层 螺旋CTA与超声造影联合应用在颈动脉斑 块稳定性具有积极作用，可显著提高诊断 准确率。

Objective To investigate the clinical application of multi-slice spiral CTA combined with contrast-enhanced ultrasound (CEUS) in the stability evaluation of carotid plaque. Methods A total of 120 cases of patients with carotid plaque stenosis admitted to our hospital from February 2017 to May 2018 were selected, and they were given carotid CTA and CEUS. The carotid plaque conditions were observed. Results Take DSA the golden standard, the consistency accuracy of CEUS examination was 88.33%, and the sensitivity and specificity were 72.73% and 94.25%, and Kappa=0.70, P<0.05. The accuracy of CTA was 81.66%, and the sensitivity and specificity were 60.00% and 90.59%, and Kappa=0.533, P<0.05. The accuracy of CTA combined with CEUS was 91.67%, and the sensitivity and specificity were 78.79% and 96.55%, and Kappa=0.783, P<0.05. The accuracy, sensitivity, specificity, negative predictive value and positive predictive value of CTA combined with CEUS were higher than those of CTA alone and CEUS alone. Conclusion Multi-slice spiral CTA combined with contrast-enhanced ultrasound has positive effects on carotid plaque stability, and can significantly improve the diagnostic accuracy.