简体中文

论著-头颈部

CTA对股动脉显著性 狭窄后侧枝循环的 研究

作者:潘志斌 宋云龙 王 萍 吴 瑶 李继元 陈 燚 吴苏蒙

所属单位:空军总医院磁共振科 (北京 100142)

PDF

摘要

目的 探讨CTA所评估的股动脉 显著性狭窄(大于50%)后股深动脉侧枝循 环的作用。方法 回顾性分析45例股动脉 显著性狭窄组患者与40例健康对照组的 CTA。统计病例组来自同侧股深动脉代偿 的征象,即旋股外侧动脉降支(和)或股 深动脉降支偏利现象(与对侧相比血管增 粗,分支增多或直接与股动脉直接相通) 的出现频率,并与对照组进行比较。同时 记录45例病例组偏利现象的评分及股动脉 狭窄的程度,对不同的狭窄程度分组并进 行组间比较分析。结果 病例组病变同侧 股深动脉偏利现象的出现频率明显高于对 照组(P<0.1)。不同狭窄组之间偏利现象 的评分差异有统计学意义(P<0.1),狭窄 程度由小到大其偏利现象的评分依次降 低。结论 股动脉显著性狭窄后,CTA可以 通过观察病变同侧股深动脉及其分支偏利 现象间接评价来自旋股外侧动脉降支和 (或)股深动脉降支的侧枝循环状况。CTA 所评价的股动脉显著性狭窄与侧枝循环 之间有密切的相关性。CTA准确评价股动 脉狭窄程度及侧枝循环情况对临床的诊治 及预后周围动脉闭塞性疾病重要的指导意 义。

Objective To investigate the role of CTA in evaluation of peripheral collateral circulation after femoral artery significant stenosis. Methods CTA fingdings were retrospecitvely reviewed in 45 patients with femoral artery significant stenosis and 40 healthy control subjects. Frequency of descending branch of lateral circumflex femoral artery and descending branch of arteria profunda femoral laterality at CTA in patients and that in healthy control subjects were compared. The descending branch of lateral circumflex femoral artery and descending branch of arteria profunda femoral laterality represents the existence of collateral circulation.Meanwhile, The descending branch of lateral circumflex femoral artery and descending branch of arteria profunda femoral laterality were scored,and the degree of stenosis of femoral artery was recorded,then divided them into three groups according to degree of stenosis ,and the groups were compared with each other. Results Frequency of arteria profunda femoral laterality in patients are much higher than that in healthy control subjects(P<0.1). There are statistic differences between scores of arteria profunda femoral laterality of each two groups. Conclusion After femoral artery significant stenosis, the laterality of arteria profunda femoral at CTA can be used to investigate the collateral circulation from the the descending branch of lateral circumflex femoral artery and descending branch of arteria profunda femoral.The collateral circulation evaluated at CTA is significantly associated with the degree of stenosis of femoral artery. CTA might play an important role in diagnosis, treatment and prognosis for patients with peripheral arterial obliterans disease.

【关键词】股动脉;侧枝循环;CTA血管 成像

【中图分类号】R543.5;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.02.036

前言

股动脉狭窄是下肢骨骼肌肉系统缺血缺氧的重要原因,尤其是有 吸烟史、高胆固醇血症、高血压或糖尿病等危险因素者,股动脉等下 肢大血管常会出现严重的管腔变窄甚至完全梗阻,远端肢体感觉异 常,影响肢体正常活动,甚至远端组织出现破溃,给患者带来生活上 和经济上的沉重负担。很多临床与影像资料表明,股动脉显著性狭窄 后,以远的血流改变以及临床表现有很大差异性。这是因为股动脉显 著性狭窄后,可以由股深动脉的分支(尤其是旋股外侧动脉降支及股深 动脉降支)部分代偿缺血区域的血液供应。因此,当股动脉显著性狭 窄后,快速、精准的评估股深动脉分支的代偿情况,对临床积极抑或 保守治疗,预后情况,都有重要的指导意义。血管数字减影术(DSA) 是评价大血管梗阻性改变的金标准,其创伤性、费用高、费时等不足 之处,仍然不适合临床的常规检查。近来临床采用的CT血管造影检查 (CTA)在诊断下肢血管梗阻性改变中的价值得到广泛认可,且逐渐成为 下肢血管疾病的首选检查。观察股动脉显著性狭窄病例的CTA,常可以 发现病变同侧的股深动脉的分支中旋股外侧动脉的降支、股深动脉的 降支出现偏利现象(与对侧相比,血管增粗、分支增多、末梢延长甚 至与股动脉狭窄以远直接相通)。目前已有文献报道[1-2],当患侧大脑 中动脉闭塞后,同侧大脑后动脉的偏利现象代表有效的侧枝代偿的形 成。而以往的文献对下肢血管的显著性狭窄后侧枝动脉的偏利现象报 导较少,对如何利用CTA来半定量评估侧枝循环的代偿情况的研究也不 多。本研究旨在观察分析CTA在评估下肢股动脉显著性狭窄后,缺血区域或远端供血来自旋股外侧动脉 降支、股深动脉降支的侧枝循环 形成的情况,并研究CTA所评估的 旋股外侧动脉降支、股深动脉降 支的侧枝代偿状况与股动脉狭窄 的严重程度之间的相关性,以期 为临床诊断及实施治疗过程中提 供可靠信息。