摘要
目的 分析矽肺并肺结核患者 临床特点及CT影像表现。方 法 选取 2014年6月至016年12月我院收治的矽肺 并肺结核患者16例,分析其发病特点、 影像表现,比较胸部X线与CT诊断准确 率及病理特征检出情况。结果 矽肺并 肺结核发病主要表现为胸闷(75.00%)、 咳嗽(56.25%)、气促(43.75%)、胸痛 (50.00%),部分患者伴盗汗、低热、 抑郁症状;X线显示胸片小阴影改变, 见团块阴影,阴影密度不均匀,边缘清 晰,周围无肺气肿,CT显示点状钙化 灶、陈旧性结合灶及双肺弥漫性间质纤 维化,病灶主要分布于血管支气管束周 围;CT诊断矽肺并肺结核的准确率明显 高于X线(P<0.05);CT对小结节影、结 核钙化及肺气肿的检出率明显高于X线(P <0.05)。结论 矽肺并肺结核以胸闷、 咳嗽、气促、胸痛伴盗汗、低热、抑郁 为主要症状,CT检查可见特征性影像学 改变,值得在临床推广应用。
Objective To analyze the clinical features and CT imaging of silicosis with pulmonary tuberculosis in 16 cases. Methods Sixteen patients with silicosis and pulmonary tuberculosis who were admitted to the hospital between June 2014 and December 2016 were enrolled in the study. Their clinical features and imaging findings were analyzed. The diagnostic accuracy and pathological characteristics were compared between chest X-ray and CT. Results The main manifestations of silicosis and pulmonary tuberculosis include chest distress (75.00%), cough (56.25%), shortness of breath (43.75%) and chest pain (50.00%). Some patients had night sweat, low-grade fever and depression. Chest X-ray showed small shadow changes, massive shadow, inhomogeneous density, clear edges and no emphysema. CT showed punctate calcification, old combined lesions and diffuse lung fibrosis in bilateral lungs. The lesions were mainly located around the vascular bundle. The accuracy of CT in the diagnosis of silicosis and pulmonary tuberculosis was significantly higher than that of X-ray (P<0.05). The detection rates of CT for small nodules, calcified tuberculosis and emphysema were significantly higher than those of X-ray (P <0.05). Conclusion The main symptoms of silicosis and pulmonary tuberculosis include chest tightness, cough, shortness of breath, chest pain, night sweats, low-grade fever and depression. CT shows typical imaging findings and it is worthy of clinical application.
【关键词】矽肺;肺结核;临床特点; CT;影像表现
【中图分类号】R521;R445.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.02.019
前言
矽肺是我国较常见且危害严重的职业病,患者长期持续吸入游离 二氧化硅粉尘并沉积于肺部,导致肺部巨噬细胞持续激活,刺激纤维 细胞增生及胶原过多沉积于肺实质内,因此矽肺为肺结核发病高危人 群,两者可相互促进,加速病情恶化,早期明确矽肺结节密度、形 态及分布范围,及时、准确地对其进行诊断,并开展治疗有重要意 义[1-2]。X线、CT为矽肺并肺结核较常见检查方法,X线多见圆形小阴 影,具有较高密度,但容易将其误诊为单纯矽肺或肺结核,CT与胸 部X线相比具有较高分辨率,还能详细了解病灶范围、分布及继发改 变[3]。本文主要分析矽肺并肺结核临床特点及CT影像表现,结果如 下。
中国CT和MRI杂志
第16卷, 第 2 期
2018年02月
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