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小肠充气螺旋CT 三维重建技术对 Peutz-Jeghers综合 征诊断价值探讨

作者:陈 燚 宋云龙 王 萍 吴苏蒙 冯 瑞

所属单位:中国人民解放军空军总医院磁共振 科 (北京 100142)

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摘要

目的 通过经肛充气灌肠法探究 多层螺旋CT对黑斑-息肉综合征(PeutzJeghers syndrome,PJS)患者小肠病变的 检出率及其临床价值。方法 对已确诊的 PJS患者30例进行经肛充气、间接充盈小 肠后进行全腹部CT扫描并行三维重建, 19例行经口小肠镜、13例行经肛小肠镜 检查。评估小肠气体充盈程度,计算CT对 病变的检出率。结果 小肠充气评分与小 肠分组之间呈正相关(P<0.001)。CT对经 肛组(下组小肠与大肠)病变检出率高于经 口组(上组小肠)(P<0.001);对上、下组 小肠病变检出率间差异无统计学意义(P> 0.05);对需要临床干预的病灶检出率为 88.2%。结论 经肛充气法对1~3组小肠 充盈程度欠佳,对4~6组小肠充盈程度较 好,可达到诊断条件;CT经肛充气灌肠对 需要临床干预的病灶有较高检出率,对临 床进镜方式的选择具有指导价值。

Objective To explore the clinical value of multi-slice spiral CT in the detection of small intestinal lesions in patients with Peutz-Jeghers syndrome(PJS). Methods 30 cases of patients diagnosed as PJS were treated by transanal insufflation and indirect filling of small intestine. Then whole abdominal CT scanning were carried out as well as three dimensional reconstruction. 19 cases underwent oral endoscopy, and 13 underwent anal endoscopy. Evaluate the filling degree of small intestine, and calculate the detection rate of CT. Results There was a positive correlation between small bowel inflation score and small bowel grouping (P<0.001). The detection rate of CT was lower than that of the oral group (upper group of small intestine) (P<0.001). The detection rate of upper group small intestine and small intestine group was not statistically significant (P>0.05). Conclusion The filling degree of transanal insufflation is not good for the 1-3 groups of small intestine but better for the 4-6 groups as regard to reliable diagnostic condition; CT transanal insufflation has a higher detection rate for the lesions needed clinical intervention, and has a guiding value for the choice of clinical endoscopic approach.

【关键词】充气;螺旋CT;Peutz- Jeghers;小肠;仿真内镜; 三维重建

【中图分类号】R445.3;R596.1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.02.010

前言

Peutz-Jeghers综合征(Peutz-Jeghers syndrome,PJS)即黑斑-息 肉综合征,是一种以皮肤色素沉着及胃肠道多发息肉为特征的常染色 体显性遗传疾病。病变可分布于整个消化道,以小肠多见[1-2],而小肠 迂曲冗长、检查方法局限,使小肠内病变的检出成为难题。本文旨在 探讨与评价一次性经肛充气法小肠螺旋CT检查,并行三维重建及结合 仿真内镜技术对小肠息肉的诊断价值。