简体中文

论著-头颈部

MRI对食管癌T分期 诊断及手术切除中 的评估价值分析*

作者:秦福双

所属单位:河南省濮阳市安阳地区医院 (河南 濮阳 455000)

PDF

摘要

目的 分析磁共振成像(MRI)对 食管癌T分期诊断及手术切除中的评估价 值。方法 选取2013年6月至2015年2月我 院收治的食管癌患者48例为研究对象,均 行CT、MRI检查,观察食管癌不同T分期的 MRI表现特点,进行术前TN分期,并以术 后病理结果为准,比较MRI、CT诊断食管 癌T分期的灵敏度、特异度、准确度及对 区域淋巴结转移的准确率。结果 MRI显示 病灶在MR-DWI上均呈高信号,T1-2期病灶 周边肌层线状低至中等信号影完整,T3期 病灶周边肌层线状低至中等信号影中断或 消失,T4期病灶与邻近结构间脂肪间隙消 失并伴邻近结构受侵征象;MRI对食管癌 T1-2分期特异度90.00%、准确度79.17% 高于CT 60.00%、58.33%(P<0.05),对 T3-4期病灶,CT、MRI的灵敏度、特异度、 准确度比较无显著差异(P>0.05);MRI及 CT对食管癌淋巴结N分期的诊断效能无显 著差异(P>0.05)。结论 MRI在食管癌术前 分期及手术评估中具有较高价值,尤其对 T1、T2期的准确率较CT高,值得在临床推 广应用。

Objective To evaluate the value of magnetic resonance imaging (MRI) in the diagnosis of T stage and evaluation of the effects of surgical resection of esophageal carcinoma. Methods Forty-eight patients with esophageal cancer treated in our hospital between June 2013 and February 2015 were selected as the study subjects. All patients underwent CT and MRI examination, and the MRI features of esophageal cancerat different T stages were observed. TN staging was performed before surgery. With the postoperative pathological results as the standard, the sensitivity, specificity and accuracy in the diagnosis of T stage of esophageal cancer and the accuracy in the diagnosis of local lymph node metastases were compared between MRI and CT. Results MRI showed showed high signal on MR-DWI. In T1-2phase, the linear low to medium signal of muscle layersurrounding lesions was complete while in T3 phase, it was interrupted or disappeared, and in T4phase, fat spaces between lesions and adjacent structures disappeared with adjacent structures invasion. The specificity and accuracy of MRI in the diagnosis of esophageal cancer at T1-2 stage (90.00%, 79.17%) were higher than those of CT (60.0%, 58.33%) (P<0.05). There were no significant differences in the sensitivity, specificity and accuracy between MRI and CT in the diagnosis of T3-4 stage (P>0.05). There was no significant difference in the diagnostic efficacy between MRI and CT in N staging of esophageal cancer (P>0.05). Conclusion MRI is of high value in preoperative staging and evaluation of esophageal cancer, especially for T1 and T2. It is worth to be popularized and applied in clinical practice.

【关键词】MRI;食管癌;T分期;诊断

【中图分类号】R735.1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.01.029

前言

食管癌为临床常见消化道恶性肿瘤,是食管鳞状上皮异常增生引 起的恶性病变,在我国位于各种死亡病因第二位,死亡率高达17%,严 重威胁人类健康,临床诊断食管癌的传统方法是食管内镜及钡餐,后 采用手术提高患者5年生存率,然而传统检查方法仅提供间接征象判 断手术方式,应用价值受限[1-2]。MRI为一种无辐射、无创伤的检查方 法,随高分辨率三维稳态扰相成像序列、扩散加权成像(DWI)、动态 增强磁共振成像(DCEMRI)等功能成像的开发,不仅缩短了成像时间, 同时提高成像质量,国外有研究应用MRI中DWI检查提供有用标记物来 预测食管癌放化疗的病理反应及患者生存率,但目前在国内应用较 少[3-5]。本文选取我院收治的食管癌患者48例为研究对象,分析MRI对 食管癌T分期诊断及手术切除中的评估价值,现报告如下。