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T2* Mapping对正常青年人骶髂关节骨髓的初步评估*

作者:刘玉涛1 李淑明1 洪国斌2 杜中立1 张 洁1 罗玉英1

所属单位:1.暨南大学医学院第三附属医院 (珠海市人民医院)放射科 (广东 珠海 519000) 2.中山大学第五附属医院放射科 (广东 珠海 519000)

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摘要

目的探讨T2* Mapping成像技 术量化评估骶髂关节软骨下骨髓含水量 的可行性。方法 对30例青年志愿者骶髂 关节行MR 16回波GRE序列的T2* Mapping 成像,分别测量骶侧上下区域和髂侧上 下区域及L5椎体下终板区域的骨髓T2* 值,对比各区域间、髂侧和骶侧及L5椎 体下终板区域间的骨髓T2*值差异,分 析骶髂关节软骨下骨髓含水量的细微差 异。结果 骶髂关节的髂侧T2*值均值为 23.08±2.9ms,骶侧为21.09±3.43ms, 髂侧骨髓平均T2*值大于骶侧(P<0.05); L5椎体下终板骨髓T2 * 值均值为 18.55±5.5ms,分别小于髂侧和骶侧骨 髓平均T2*值(P<0.05);而左右髂骨上下 区域间(RI1/RS1,LI4/LS4,RI1/LI4, RS1/LS4)T2*值对比无差异(P>0.05),左 右骶骨上下区域间(RI2/RS2,LI3/LI3, LI3/RI2,LS3/RS2)T2*值对比也无统计学 意义(P>0.05)。结论 正常青年人骶髂关 节软骨下骨髓含水量髂侧多于骶侧,髂 侧和骶侧均多于L5椎体下终板区域,T2* mapping成像技术对骶髂关节软骨下骨髓 的核磁共振含水量进行细微量化评估是可 行的。

Objective To investigate the feasibility of Mapping T2* imaging in the evaluation of the feasibility of the bone marrow of the bone marrow. Methods Mapping T2* imaging was performed on 30 cases of young volunteers with MR 16 echo GRE sequence of L5, and the T2* values of bone marrow T2* were measured in the upper and lower regions of the sacral region and the lower end of the L5. Results The mean value of T2* in the iliac side of the di joint was 23.08+2.9ms sacral 21.09+3.43ms, iliac bone marrow T2* in the sacral side (P<0.05); L5 vertebral endplate bone marrow T2* values is 18.55+5.5ms, respectively less than iliac and sacral bone marrow side T2* values (P<0.05); and the left iliac bone area (ri1/RS1 LI4/Ls4 ri1/LI4 RS1/Ls4) T2* values compared to no difference (P>0.05), left and right sacrum region (RI2/RS2 Li3/Li3, Li3/RI2 LS3/ RS2 T2* value contrast is also no statistical significance (P>0.05). Conclusion The bone marrow of normal young people with the bone marrow contains more than the sacral side, and the iliac and sacral sides are more than the lower end of the L5 vertebral body. T2* mapping imaging technique is feasible for the evaluation of the content of the bone marrow

【关键词】核磁共振;骶髂关节;T2* Mapping

【中图分类号】R322.7+2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.04.037

前言

骶髂关节是强直性脊柱炎最早累及的部位,其软骨下骨髓水肿是 AS在MR早期诊断的重要征象之一[1,2],如何准确地量化骨髓水肿的程 度,尤其髂侧和骶侧软骨下骨髓含水量的正常值对客观评估骨髓水肿 有着重要的临床意义,但目前对骶髂关节骨髓水肿的量化评估仍缺乏 精准,易行,有效的手段[3]。本研究通过测量青年人骶侧和髂侧及L5 椎体骨髓的T2*值,量化分析骶髂关节软骨下正常骨髓的含水量,探讨 T2* Mapping成像技术评估骶髂关节软骨下骨髓含水量的可行性。