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浸润性宫颈癌术前CT及MRI诊断的临床价值研究

作者:张秋芳 连 鹏

所属单位:陕西省西安市第四医院影像科(陕西 西安 710004)

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摘要

目的比较分析术前CT、MRI对 浸润性宫颈癌的诊断临床价值。方法 以 我院2014年1月-2015年12月经手术病理 证实的41例浸润性宫颈癌患者为研究对 象,所有患者术前行CT、MRI检查,以术 后病理分期为对照,比较CT、MRI对宫 颈癌术前分期的诊断价值。同时以术后 病理学检查结果对照,比较CT、MRI对 阴道浸润、淋巴结转移等相关征象诊断 敏感度、特异度及准确度。结果 以术 后病理分期为对照,术前CT对病变临床 分期诊断符合率为75.6%,而MRI诊断符 合率为90.2%;术前MRI诊断I B1期及以 下符合率85.7%,显著高于CT的50.0%(P <0.05)。对照术后病理各征象结果,CT 对阴道浸润诊断准确率68.3%,显著低于 MRI的90.2%(P<0.05);CT对子宫体侵 犯诊断特异度、准确度分别为100.0%、 97.6%,显著高于MRI的87.1%、85.4%(P <0.05);CT对盆腔淋巴结转移诊断特异 度、准确度分别为100.0%、92.7%,显著 高于MRI的81.5%、70.7%(P<0.05)。结 论 术前MRI对浸润性宫颈癌IIA以下分期 诊断价值明显优于CT,而对IIA以上病变 诊断价值不如CT。MRI在阴道浸润诊断方 面准确率更高,而CT在子宫体侵犯、盆 腔淋巴结转移方面诊断更有价值。

Objective To compare the clinical value of preoperative CT and MRI in the diagnosis of invasive cervical cancer. Methods 41 patient with invasive cervical cancer confirmed by surgery and pathology in our hospital from January 2014 to December 2015 were treated as the study object. All patients underwent MRI and CT examination before operation. Taking postoperative pathological staging as control, the diagnostic value of CT and MRI in preoperative staging of cervical cancer was compared. Meanwhile, the results of postoperative pathological examination were taken as control to the sensitivity, specificity and accuracy of MRI and CT in the diagnosis of vaginal invasion, lymph node metastasis and other signs. Results Taking postoperative pathological staging as the control, the coincidence rate of preoperative CT in diagnosis of clinical staging was 75.6% while of MRI was 90.2%; The coincidence rate of preoperative MRI in diagnosis of I B1 stage and below (85.7%) was significantly higher than that of CT (50.0%) (P<0.05). Compared with the postoperative pathological signs, the accuracy rate of CT in diagnosis of virginal invasion (68.3%) was significantly lower that of MRI (90.2%) (P<0.05); The specificity and accuracy of CT in the diagnosis of uterine body invasion (100.0%, 97.6%) were significantly higher than those of MRI (87.1%, 85.4%) (P<0.05); The specificity and accuracy of CT in diagnosis of pelvic lymph node metastasis (100.0%, 92.7%) were significantly higher than those of MRI (81.5%, 70.7%) (P<0.05). Conclusion The diagnostic value of preoperative MRI in IIA or below stage of invasive cervical cancer is significantly better than CT while in the diagnosis of IIA or above lesions is not as good as CT. MRI is more accurate in the diagnosis of vaginal infiltration and CT is more valuable in the diagnosis of uterine body invasion and pelvic lymph node metastasis

【关键词】浸润性宫颈癌;CT;MRI;术前分期;征象

【中图分类号】R445.2;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.04.032

前言

流行病学显示,全世界1年新增宫颈癌46.5万,目前我国宫颈癌病 例有40多万,病死率10%左右,明显比发达国家高,且近年来我国浸润 性宫颈癌发病率不断增多,严重影响女性患者生活质量[1]。为此早期 正确诊断、治疗宫颈癌至关重要,其中治疗方案制定与病变临床分期 有关,而临床分期对宫旁浸润诊断准确率较低,为此需借助影像学检 查对原发肿瘤、宫旁浸润及远处淋巴结转移准确显示[2]。目前临床常 见影像学方法为CT、MRI,两者组织分辨率均较高,其中CT最大优点为 后处理技术强大,MRI可多方面、多序列成像,在宫颈癌诊断中应用较 多,各有优劣。为了选择最佳影像学检查手段,本研究通过与术后病 理结果对照,比较分析CT、MRI对浸润性宫颈癌术前临床分期及各征象 诊断价值。现报告如下。