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FFDM表现为肿块与非肿块型乳腺癌的MR-DCE诊断分析

作者:李逢芳1 陈慧铀1 王 瑞2

所属单位:1.南京医科大学附属南京医院放射 科 (江苏 南京 210006) 2.东南大学附属中大医院放射科 (江苏 南京 210009)

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摘要

目的 探讨磁共振动态增强扫描 在FFDM表现为肿块与非肿块型乳腺癌中的 不同表现及诊断价值。方法 回顾性收集 本院经病理证实的乳腺癌患者共89例, 按 FFDM表现分为肿块型(62例)与非肿块型 (27)例,均行MR动态增强扫描,分析比较 两组乳腺癌的形态学、早期强化率、峰 值强化率及时间-信号曲线类型的表现特 征。结果 (1)形态学表现:62例肿块型 乳腺癌主要表现为均匀强化43(39.4%), 其次表现为不均匀强化13(21.0%)、边缘 强化6(9.6%);27例非肿块型表现为不均 匀强化9(33.3%)、均匀强化18(66.7%), 且二者差异有统计学差异。(2)肿块与 非肿块型乳腺癌的早期强化率分别为 198.83±38.51%、143.59±39.22%; 峰值强化率分别为209.55±40.24%、 157.31±35.02%,且两者存在显著性统计 学差异(P<0.05)。(3)TIC曲线类型:62例 肿块型乳腺癌中,Ⅰ型曲线5例(8.1%)、 Ⅱ型49例(79%)、Ⅲ型8例(12.9%); 27例非肿块型乳腺癌肿,Ⅰ型曲线8例 (29.6%)、Ⅱ型15例(55.6%)、Ⅲ型4例 (14.8%),且两者存在显著性统计学差异 (P<0.05)。结论 MR动态增强形态学表 现、定量指标及曲线类型在肿块与非肿块 型乳腺癌中的分布均具有统计学意义,对 诊断有较大意义。

Objective To investigate the different manifestations and the diagnostic value of MRI diffusion weighted imaging for the palpable or nonpalpable breast cancer. Methods 89 cases of malignant breast tumors (62 cases of palpable, 27 cases of nonpalpable) were underwent with dynamic contrast-enhanced MR in our hospital. The morphlolgical performance, early enhanced rate, peak enhanced rate and time-signal curve type were analysised and compared. Results (1) morphological manifestations: 62 cases of palpable breast cancer tumors showed heterogeneous enhancement 13 (21.0%), homogeneous enhancement 43 (39.4%), edge enhancement in 6 (9.6%); 27 cases of nonpalpable showed heterogeneous enhancement 9 (33.3%), statistically significant 18 (66.7%), and the difference between the two.(2)The early enhanced rate of palpable and nonpalpable breast cancer were 198.83±38.51%, 143.59±39.22%, the peak enhanced rate cancer were 209.55±40.24%、157.31±35.02%, There were statistically significant differences (P<0.05) in the early enhanced rate and peak enhanced rate between the two group breast cancer .(3)TIC type: there were Ⅰ type curve 5 cases (8.1%), type Ⅱ49 (79%), Ⅲ 8 cases (12.9%) in 62 cases of palpable breast cancer; there wereⅠcurve 8 cases (29.6%), type Ⅱ 15 (55.6%), Ⅲ 4 cases (14.8%) in 27 cases of nonpalpable breast cancer, and there was a significant difference (P<0.05) between the two group. Conclusion There were statistically significant in morphologic features, quantitative parameters and TIC type of the palpable and nonpalpable breast cancer, the morphologic features, quantitative parameters and TIC type of dynamic contrast enhanced MRI are valuable in the diagnosis of palpable and nonpalpable breast cancer

【关键词】乳腺癌;动态增强磁共振成像;肿块与非肿块

【中图分类号】R445.2;R737.9

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.04.011

前言

乳腺动态增强扫描(dynomic contrast enhanced magnetic reasonance imaging,DCE-MRI)在乳腺良恶性病变的鉴别诊断上发挥着 重要作用,为更好的评价病灶的形态及血流动力学特征提供了基础。 动态增强扫描参数较多,主要包括三个方面:增强后形态学特征、增 强定量指标及曲线类型,可以从不同方面反映乳腺肿块的血流血运特 点。关于乳腺良恶性病变DCE-MRI的表现文献报道较多,但关于肿块与 非肿块型乳腺癌的DCE-MRI表现文献报道较少,本文主要是比较分析肿 块与非肿块型乳腺癌在以上这三个方面的表现特点及差异。